Caspase-7 Antibody_单克隆抗体-上海泊湾生物技术有限公司

Caspase-7 Antibody

Source: Rabbit mAb Catalog No. : CY5579

Caspase-7 Antibody (CY5579)
UniProt:P97864(mouse)(human:P55210 )
Application:WB,IHC,IP
Reactivity:Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5579

 Datasheet

数据表

UniProt

P97864(mouse)(human:P55210 )
Mol Weight

34kDa
Alternative Names

CMH-1; ICE-LAP3; MCH3; CASP7; Caspase-7; Caspase7;
Immunogen

A synthesized peptide derived from human Caspase-7
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis. Caspase-7 is an effector caspase (along with caspase-2 and -3), meaning that it cleaves essential cellular machinery rather than activating other caspases. Caspase-7 is cleaved by many enzymes, including caspases-3, -6, -8, -9 and granzyme B. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase, or PARP.

Applications

Reactivity

Mouse,Rat
Application

WB,IHC,IP
Recommended dilution

WB 1:500~1:1000 IHC 1:50~1:200 IP 1:50

Western blot analysis of Caspase-7 expression in NIH/3T3 cell lysate.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

引用文献（1条）

Lysine demethylase KDM3A regulates nanophotonic hyperthermia resistance generated by 2D silicene in breast cancer-Biomaterials