Phospho-TrkB (Y817) Antibody
Source: Rabbit mAb Catalog No. : CY5598
Phospho-TrkB (Y817) Antibody (CY5598)
UniProt:Q16620
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（2）
http://www.abways.cn/showproduct.asp?cid=CY5598
数据表
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UniProt
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Mol Weight140kDa
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Alternative NamesNTRK2; gp145-TrkB; Trk-B; TRKB; Tropomyosin-related kinase B; TrkB tyrosine kinase; Tyrosine kinase receptor B;
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ImmunogenA synthesized peptide derived from human Phospho-TrkB (Y817)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:1000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30
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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of Phospho-TrkB (Y817) expression in SH-SY5Y cell lysate treated with BDNF. -
Immunohistochemical analysis of paraffin-embedded mouse brain cancer, using Phospho-TrkB (Y817) Antibody.
引用文献（2条）
miR-34a induces spine damages via inhibiting synaptotagmin-1 in depression-Neurobiology of Stress (NEUROBIOL STRESS)
Antidepressant-like Effects of Degraded Porphyran Isolated from Porphyra haitanensis-MOLECULAR NUTRITION & FOOD RESEARCH (Mol. Nutr. Food Res)
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