Tuberin Antibody
Source: Rabbit mAb Catalog No. : CY5601
Tuberin Antibody (CY5601)
UniProt:P49815
Application:WB,IHC,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5601
数据表
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UniProt
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Mol Weight200kDa
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Alternative NamesTSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin;
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ImmunogenA synthesized peptide derived from human Tuberin
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 FC 1:50
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Western blot analysis of Tuberin expression in Jurkat cell lysate. -
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using Tuberin Antibody. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
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