GRK2 Antibody
Source: Rabbit mAb Catalog No. : CY5602
GRK2 Antibody (CY5602)
UniProt:P25098
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5602
数据表
-
UniProt
-
Mol Weight80kDa
-
Alternative NamesGRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1;
-
ImmunogenA synthesized peptide derived from human GRK2
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityMonoclonal
-
DescriptionGRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin.
Applications
-
ReactivityHuman,Mouse,Rat
-
ApplicationWB,IHC
-
Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200
-
Western blot analysis of GRK2 expression in THP-1 cell lysate.
销售咨询
一键电话