Caspase-6 Antibody
Source: Rabbit mAb Catalog No. : CY5609
Caspase-6 Antibody (CY5609)
UniProt:P55212
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5609
数据表
-
UniProt
-
Mol Weight11,33kDa
-
Alternative NamesMCH2; CASP6; Caspase-6;
-
ImmunogenA synthesized peptide derived from human Caspase-6
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityMonoclonal
-
DescriptionCaspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.
Applications
-
ReactivityHuman,Mouse,Rat
-
ApplicationWB,IHC,ICC/IF,IP
-
Recommended dilutionWB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
-
Western blot analysis of Caspase-6 expression in Jurkat cell lysate. -
Immunohistochemical analysis of paraffin-embedded human colon, using Caspase-6 Antibody. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
销售咨询
一键电话