FGFR1 Antibody
Source: Rabbit mAb Catalog No. : CY5610
FGFR1 Antibody (CY5610)
UniProt:P11362
Application:WB,ICC/IF
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5610
数据表
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UniProt
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Mol Weight120, 140kDa
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Alternative NamesBFGFR; CD331; CEK; FGFBR; FLG; FLJ99988; FLT2; HBGFR; KAL2; N-SAM; OGD;FGF Receptor 1;
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ImmunogenA synthesized peptide derived from human FGFR1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionFibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766.
Applications
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ReactivityHuman
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ApplicationWB,ICC/IF
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Recommended dilutionWB 1:500~1:1000 ICC/IF 1:50~1:200
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Immunohistochemical analysis of paraffin-embedded Human pituitary tumor, using the Antibody at 1:50 dilution. -
Immunohistochemical analysis of paraffin-embedded Human thymoma, using the Antibody at 1:50 dilution. -
Immunohistochemical analysis of paraffin-embedded Rat pancreas, using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:150 dilution. -
Western blot analysis of FGFR1 expression in SH-SY5Y cell lysate. -
Immunofluorescent analysis of HeLa cells, using FGFR1 Antibody.
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