5T4 Antibody
Source: Rabbit mAb Catalog No. : CY5612
5T4 Antibody (CY5612)
UniProt:Q13641
Application:WB,IHC
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5612
数据表
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UniProt
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Mol Weight80kDa
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Alternative NamesTPBG; 5T4; 5T4-AG; 5T4AG; 5T4 oncofetal antigen; M6P1; Trophoblast glycoprotein;
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ImmunogenA synthesized peptide derived from human 5T4
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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Description5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
Applications
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ReactivityHuman
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:1000 IHC 1:50~1:200
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Western blot analysis of 5T4 expression in Caco-2 cell lysates. -
Immunohistochemical analysis of paraffin-embedded human uters cancer, using 5T4 Antibody.
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