Phospho-EGFR (Y1197) Antibody
Source: Rabbit mAb Catalog No. : CY5614
Phospho-EGFR (Y1197) Antibody (CY5614)
UniProt:P00533
Application:WB,IHC,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5614
数据表
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UniProt
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Mol Weight175kDa
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Alternative NamesEC 2.7.10.1; ERBB1; Epidermal growth factor receptor precursor; kinase EGFR;
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ImmunogenA synthesized peptide derived from human EGFR Full-length sequence 1210aa around the phosphorylation site of Tyrosine 1197
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysosomal degradation. The GRB2 adaptor protein binds activated EGFR at phospho-Tyr1068.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:20
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Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of Phospho-EGFR (Y1197) expression in A431 cell lysate treated with EGF. -
Immunohistochemical analysis of paraffin-embedded rat stomach, using Phospho-EGFR (Y1197) Antibody. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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