ERR alpha Antibody
Source: Rabbit mAb Catalog No. : CY5617
ERR alpha Antibody (CY5617)
UniProt:P11474
Application:WB,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5617
数据表
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UniProt
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Mol Weight50kDa
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Alternative NamesESRRA; ERRa; ERR1; HERR1; NR3B1; Steroid hormone receptor ERR1; ERR-alpha; ERRalpha; ESRL1; Estrogen receptor-like 1; Estrogen-related receptor alpha;
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ImmunogenA synthesized peptide derived from human ERR alpha
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionEstrogen-related receptor alpha (ERRα/NR3B1) is an orphan nuclear receptor that controls transcription of genes involved in fatty acid oxidation, glucose metabolism, and mitochondrial biogenesis. The receptor protein contains a non-conserved amino terminal domain (NTD), a central zinc finger DNA binding domain, and a ligand-binding domain. The carboxy-terminal AF2 helix motif of ERRα contains binding sites for nuclear receptor coactivators PGC-1α and PGC-1β. Research studies demonstrate that ERRα transcriptional activity is regulated through phosphorylation and sumoylation within the NTD.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IP,FC
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Recommended dilutionWB 1:1000~1:2000 IP 1:50 FC 1:20
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
Western blot analysis of ERR alpha expression in HeLa cell lysate. -
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:3K dilution)
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