Phospho-ATF2 (T71) Antibody
Source: Rabbit mAb Catalog No. : CY5627
Phospho-ATF2 (T71) Antibody (CY5627)
UniProt:P15336
Application:WB,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5627
数据表
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UniProt
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Mol Weight70kDa
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Alternative NamesATF2, Activating 2, CREB2, CREBP1, Cyclic-AMP-dependent ATF-2, HB16, MXBP protein, cAMP response element binding protein CRE-BP1;
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ImmunogenA synthesized peptide derived from human Phospho-ATF2 (T71)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71.
Applications
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ReactivityHuman
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ApplicationWB,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:30
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Western blot analysis of Phospho-ATF2 (T71) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with Anisomycin. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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