Chk2 Antibody
Source: Rabbit mAb Catalog No. : CY5633
Chk2 Antibody (CY5633)
UniProt:O96017
Application:WB,IHC,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5633
数据表
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UniProt
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Mol Weight62kDa
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Alternative NamesCHEK2; CHK2; Cds1; Chk2; EC 2.7.11.1; RAD53; kinase Chk2;
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ImmunogenA synthesized peptide derived from human Chk2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThese are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:10000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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Western blot analysis of Chk2 expression in (1) HeLa cell lysate; (2) 293T cell lysate. -
Immunohistochemical analysis of paraffin-embedded human testis, using Chk2 Antibody. -
Immunofluorescent analysis of Hela cells, using Chk2 Antibody. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature.
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