JAM1 Antibody
Source: Rabbit mAb Catalog No. : CY5635
JAM1 Antibody (CY5635)
UniProt:Q9Y624
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5635
数据表
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UniProt
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Mol Weight33kDa
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Alternative NamesF11R;CD321;JAM;JAM-1;JAM-A;JAM1;JAMA;JCAM;KAT;PAM-1;Junction adhesion molecule 1;
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ImmunogenA synthesized peptide derived from human JAM1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionSeems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200
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Western blot analysis of JAM1 expression in HeLa cell lysate. -
Immunohistochemical analysis of paraffin-embedded human blader cancer, using JAM1 Antibody. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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