p63 Antibody_单克隆抗体-上海泊湾生物技术有限公司

p63 Antibody

Source: Rabbit mAb Catalog No. : CY5659

p63 Antibody (CY5659)
UniProt:Q9H3D4
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5659

 Datasheet

数据表

UniProt

Q9H3D4
Mol Weight

35-77kDa
Alternative Names

EEC3; KET; LMS; SHFM4; TA p63 alpha; TP63; p51; p73H; p73L; tumor protein p63;
Immunogen

A synthesized peptide derived from human p63
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis.

Applications

Reactivity

Human,Mouse,Rat
Application

WB,IHC,ICC/IF,FC
Recommended dilution

WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:500

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody at 1:500 dilution.
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:500 dilution.
Immunohistochemical analysis of paraffin-embedded Human small cell lung cancer , using the Antibody at 1:500 dilution.
Western blot analysis of p63 expression in A431 cell lysate.
Immunohistochemical analysis of paraffin-embedded human breast, using p63 Antibody.
Immunofluorescent analysis of A431 cells, using p63 Antibody.

引用文献（1条）

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma-Cell Death & Disease (CELL DEATH DIS)