P06400

105kDa

OSRC; RB; p105-Rb; RB1; pRb; pp110;

A synthesized peptide derived from human Retinoblastoma

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Monoclonal

The retinoblastoma tumor suppressor protein, Rb, regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle. Rb has three functionally distinct binding domains and interacts with critical regulatory proteins including the E2F family of transcription factors, c-Abl tyrosine kinase, and proteins with a conserved LXCXE motif. Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression.

Human,Mouse

WB,IHC,ICC/IF,IP

WB 1:1000~1:2000 IHC 1:100~1:500 ICC/IF 1:100~1:500 IP 1:50