Phospho-MSK1 (S376) Antibody
Source: Rabbit mAb Catalog No. : CY5663
Phospho-MSK1 (S376) Antibody (CY5663)
UniProt:O75582
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5663
数据表
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UniProt
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Mol Weight90kDa
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Alternative Names90 kDa ribosomal protein S6 kinase polypeptide 5; EC 2.7.11.1; KS6A5; MSPK1; Nuclear mitogen- and stress-activated protein kinase-1; RLPK; RPS6KA5; kinase MSK1; ribosomal protein S6 kinase;
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ImmunogenA synthesized peptide derived from human Phospho-MSK1 (S376)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionSerine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.
Applications
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ReactivityHuman,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF1:50~1:200 IP 1:50
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Western blot analysis of Phospho-MSK1 (S376) expression in HEK293 cell lysate treated with EGF. -
Immunohistochemical analysis of paraffin-embedded human lung cancer, using Phospho-MSK1 (S376) Antibody.
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