Phospho-RPA2 (T21) Antibody
Source: Rabbit mAb Catalog No. : CY5664
Phospho-RPA2 (T21) Antibody (CY5664)
UniProt:P15927
Application:WB,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5664
数据表
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UniProt
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Mol Weight32kDa
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Alternative NamesREPA2; RF-A; RP-A; RPA2; RPA32; replication factor-A protein 2; replication protein A 32 kDa subunit; replication protein A2;
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ImmunogenA synthesized peptide derived from human Phospho-RPA2 (T21)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionAs part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IP
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Recommended dilutionWB 1:5000~1:10000 IP 1:20
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Western blot analysis of Phospho-RPA2 (T21) expression in HeLa cell lysate treated with Calyculin A.
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