Smac/Diablo Antibody
Source: Rabbit mAb Catalog No. : CY5705
Smac/Diablo Antibody (CY5705)
UniProt:Q9NR28
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5705
数据表
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UniProt
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Mol Weight21kDa
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Alternative NamesSMAC; DFNA64; DIABLO; SMAC3;
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ImmunogenA synthesized peptide derived from human Smac/Diablo
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionSmac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50 FC 1:50
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Western blot analysis of Smac/Diablo expression in Jurkat cell lysate. -
Immunohistochemical analysis of paraffin-embedded human kidney, using Smac/Diablo Antibody.
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