Glutaminase Antibody
Source: Rabbit mAb Catalog No. : CY5719
Glutaminase Antibody (CY5719)
UniProt:O94925
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5719
数据表
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UniProt
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Mol Weight65,73kDa
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Alternative NamesGlutaminase kidney isoform; GLS; GLS1, KGA; K-glutaminase; GAM; GAC; Glutaminase C; L-glutamine amidohydrolase;
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ImmunogenA synthesized peptide derived from human Glutaminase
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionCatalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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Western blot analysis of Glutaminase expression in 293T cell lysate. -
Immunohistochemical analysis of paraffin-embedded human brain, using Glutaminase Antibody. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
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