Phospho-YAP1 (S127) Antibody
Source: Rabbit mAb Catalog No. : CY5743
Phospho-YAP1 (S127) Antibody (CY5743)
UniProt:P46937
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（2）
http://www.abways.cn/showproduct.asp?cid=CY5743
数据表
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UniProt
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Mol Weight65kDa
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Alternative Names65 kDa Yes associated protein; YAP; YAp 1; YAP2; YAP 65;YKI; Yorkie homolog;
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ImmunogenA synthesized peptide derived from human YAP1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionYAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:5000~1:20000 IHC 1:50~1:200
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Western blot analysis of Phospho-YAP1 (S127) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with FBS+calyculin A. -
Immunohistochemical analysis of paraffin-embedded human stomach, using Phospho-YAP1 (S127) Antibody.
引用文献（2条）
A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties-Journal of Hematology & Oncology (J HEMATOL ONCOL)
Yes-associated protein inhibition ameliorates liver fibrosis and acute and chronic liver failure by decreasing ferroptosis and necroptosis-Heliyon
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