Cyclin E2 Antibody
Source: Rabbit mAb Catalog No. : CY5821
Cyclin E2 Antibody (CY5821)
UniProt:O96020
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5821
数据表
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UniProt
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Mol Weight47kDa
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Alternative NamesCCN E2; CCNE 2; CCNE2 protein; CYC E2; CYCE 2; CyclinE2; G1/S specific cyclin E2;
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ImmunogenA synthesized peptide derived from human Cyclin E2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionCyclin E1 and cyclin E2 can associate with and activate CDK2. Upon DNA damage, upregulation/activation of the CDK inhibitors p21 Waf1/Cip1 and p27 Kip1 prevent cyclin E/CDK2 activation, resulting in G1/S arrest. Essential for the control of the cell cycle at the late G1 and early S phase.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:100~1:500 FC 1:20
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Western blot analysis of Cyclin E2 expression in HeLa cell lysate. -
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using Cyclin E2 Antibody. -
Immunofluorescent analysis of Hela cells, using Cyclin E2 Antibody. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.
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