IRS1 Antibody
Source: Rabbit mAb Catalog No. : CY5830
IRS1 Antibody (CY5830)
UniProt:P35568
Application:WB,IHC,ICC/IF
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5830
数据表
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UniProt
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Mol Weight170kDa
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Alternative NamesHIRS1; Insulin receptor substrate 1; IRS 1; IRS1;
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ImmunogenA synthesized peptide derived from human IRS1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionIRS1 is one of the major substrates of the insulin receptor kinase. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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Western blot analysis of IRS1 expression in HEK293 cell lysate. -
Immunofluorescent analysis using the Antibody at 1:25 dilution. -
Immunofluorescent analysis using the Antibody at 1:25 dilution. -
Immunofluorescent analysis using the Antibody at 1:100 dilution.
引用文献（1条）
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats.-Free Radical Biology and Medicine
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