PDPK1 Antibody
Source: Rabbit mAb Catalog No. : CY5834
PDPK1 Antibody (CY5834)
UniProt:O15530
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5834
数据表
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UniProt
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Mol Weight63kDa
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Alternative Names3-phosphoinositide dependent protein kinase-1; EC 2.7.11.1; hPDK1; kinase PDK1; mPDK1; PDPK1; PkB kinase; Protein kinase B kinase;
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ImmunogenA synthesized peptide derived from human PDPK1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPhosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:1000~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200
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Western blot analysis of PDPK1 expression in HEK293 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human kidney, using PDPK1 Antibody. -
Immunofluorescent analysis of PC-12 cells, using PDPK1 Antibody.
引用文献（1条）
Fibulin-3 has anti-tumorigenic activities in cutaneous squamous cell carcinoma.-Journal of Investigative Dermatology
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