Phospho-PLK1 (T210) Antibody
Source: Rabbit mAb Catalog No. : CY5844
Phospho-PLK1 (T210) Antibody (CY5844)
UniProt:P53350
Application:WB
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5844
数据表
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UniProt
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Mol Weight68kDa
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Alternative NamesCell cycle regulated protein kinase; PLK 1; PLK; Polo like kinase 1 ; Serine/threonine protein kinase 13; Serine/threonine protein kinase PLK1; STPK 13;
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ImmunogenA synthesized peptide derived from human PLK1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionRequired for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:1000~1:2000
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Western blot analysis of Phospho-PLK1 (T210) expression in (1) HeLa cell lysate; (2) HeLa cell treated with nocodazole lysate.
引用文献（1条）
Novel Dual BET and PLK1 Inhibitor WNY0824 Exerts Potent Antitumor Effects in CRPC by Inhibiting Transcription Factor Function and Inducing Mitotic Abnormality-Molecular Cancer Therapeutics (MOL CANCER THER)
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