Phospho-AMPK alpha 1 (S496) Antibody_单克隆抗体-上海泊湾生物技术有限公司

Phospho-AMPK alpha 1 (S496) Antibody

Source: Rabbit mAb Catalog No. : CY5882

Phospho-AMPK alpha 1 (S496) Antibody (CY5882)
UniProt:Q13131
Application:WB,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5882

 Datasheet

数据表

UniProt

Q13131
Mol Weight

64kDa
Alternative Names

5'-AMP-activated protein kinase catalytic subunit alpha-1; AAPK1; AMP-activate kinase alpha 1 subunit; AMP-activated protein kinase; AMPK; AMPK alpha 1; AMPK subunit alpha-1; PRKAA 1; ACACA kinase;
Immunogen

A synthesized peptide derived from human AMPK alpha 1
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. Accumulating evidence indicates that AMPK not only regulates the metabolism of fatty acids and glycogen, but also modulates protein synthesis and cell growth through EF2 and TSC2/mTOR pathways, as well as blood flow via eNOS/nNOS.

Applications

Reactivity

Human
Application

WB,ICC/IF,IP
Recommended dilution

WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:50

Western blot analysis of Phospho-AMPK alpha 1 (S496) expression in (1) 293T cell lysate treated with LP; (2) 293T cell lysate.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

引用文献（1条）

Inhibition of neointima hyperplasia by the combined therapy of linagliptin and metformin via AMPK/Nox4 signaling in diabetic rats-Free Radical Biology and Medicine