NOTCH4 Antibody
Source: Rabbit mAb Catalog No. : CY5939
NOTCH4 Antibody (CY5939)
UniProt:Q99466
Application:WB,FC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5939
数据表
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UniProt
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Mol Weight230kDa
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Alternative NamesNOTC4; hNotch4; INT3; Notch homolog 4;
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ImmunogenA synthesized peptide derived from human NOTCH4
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionFunctions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
Applications
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ReactivityHuman,Mouse
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ApplicationWB,FC
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Recommended dilutionWB 1:100~1:500 FC 1:50
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Western blot analysis of NOTCH4 expression in Mouse lung lysate.
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