Cdc23/APC8 Antibody
Source: Rabbit mAb Catalog No. : CY5947
Cdc23/APC8 Antibody (CY5947)
UniProt:Q9UJX2
Application:WB,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5947
数据表
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UniProt
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Mol Weight64kDa
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Alternative NamesCDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8;
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ImmunogenA synthesized peptide derived from human Cdc23/APC8
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionAnaphase-promoting complex subunit 8 (APC8, CDC23) is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16). APC8 protein associates with APC3 and APC6 to facilitate recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. Research studies suggest that APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,ICC/IF
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:100
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Immunofluorescent analysis using the Antibody at 1:50 dilution.
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Immunofluorescent analysis using the Antibody at 1:50 dilution.
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Western blot analysis of Cdc23/APC8 expression in (1)HepG2 cell lysate; (2)Jurkat cell lysate.
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All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature.
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All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature.
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All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature.
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.



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