PD-L1 (CD274) Antibody
Source: Rabbit mAb Catalog No. : CY5980
PD-L1 (CD274) Antibody (CY5980)
UniProt:Q9NZQ7
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5980
数据表
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UniProt
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Mol Weight46kDa
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Alternative NamesB7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274;
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ImmunogenA synthesized peptide derived from human PD-L1 (CD274)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionProgrammed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:100~1:500 IHC 1:50~1:100
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of PD-L1 (CD274) expression in Ramos cell lysate. -
Immunohistochemical analysis of paraffin-embedded human thymoma, using PD-L1 (CD274) Antibody.
引用文献（1条）
Exosomal PD-L1 functions as an immunosuppressant to promote wound healing-Journal of Extracellular Vesicles (J EXTRACELL VESICLES)
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