Phospho-mTOR (S2481) Antibody
Source: Rabbit mAb Catalog No. : CY5996
Phospho-mTOR (S2481) Antibody (CY5996)
UniProt:P42345
Application:WB
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（4）
http://www.abways.cn/showproduct.asp?cid=CY5996
数据表
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UniProt
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Mol Weight289kDa
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Alternative NamesFRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;
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ImmunogenA synthesized peptide derived from human Phospho-mTOR (S2481)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionAn atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB
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Recommended dilutionWB 1:500~1:2000
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Western blot analysis of Phospho-mTOR (S2481) expression in (1)293 cell lysate treated with LP; (2)293 cell lysate. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
引用文献（4条）
OGR1 negatively regulates β-casein and triglyceride synthesis and cell proliferation via the PI3K/AKT/mTOR signaling pathway in goat mammary epithelial cells-Animal Biotechnology (ANIM BIOTECHNOL)
Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway-Biomedicine & Pharmacotherapy (BIOMED PHARMACOTHER)
lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus - 2021.9-Cell Death and Differentiation
Atorvastatin suppresses the progression of cervical cancer via regulation of autophagy-American Journal of Translational Research (Am J Transl Res)
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