Phospho-Akt (Ser473) Antibody
Source: Rabbit pAb Catalog No. : CY6016
Phospho-Akt (Ser473) Antibody (CY6016)
UniProt:P31749/P31751/Q9Y243
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAb
References（3）
http://www.abways.cn/showproduct.asp?cid=CY6016
数据表
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UniProt
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Mol Weight56kDa
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Alternative NamesEC 2.7.11.1 RAC-PK-alpha Protein kinase B PKB C-AKT/EC 2.7.11.1 RAC-PK-beta Protein kinase Akt-2 Protein kinase B, beta PKB beta/EC 2.7.11.1 RAC-PK-gamma Protein kinase Akt-3 Protein kinase B, gamma PKB gamma STK-2
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ImmunogenA synthesized peptide derived from human Akt around the phosphorylation site of Serine 473
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionThe serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
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Western blot analysis of extracts from HeLa cells treated with heat shock, using Akt(Phospho-Ser473) Antibody. -
Immunohistochemical analysis of paraffin- embedded breast carcinoma, using Akt (Phospho-Ser473) Antibody.
引用文献（3条）
Self-Assembled/Drug-Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades-VETERINARY RESEARCH(VET RES)
Self-Assembled/Drug-Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades-VETERINARY RESEARCH(VET RES)
Acid sphingomyelinase downregulation alleviates vascular endothelial leptin resistance in rats-Acta Pharmacologica Sinica (ACTA PHARMACOL SIN)
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