Phospho-Caspase 1 (Ser376) Antibody
Source: Rabbit pAb Catalog No. : CY6078
Phospho-Caspase 1 (Ser376) Antibody (CY6078)
UniProt:P29466
Application:WB,IHC
Reactivity:Human,Mouse
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6078
数据表
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UniProt
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Mol Weight27 kDa
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Alternative NamesCASP-1, EC 3.4.22.36, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, caspase-1, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45
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ImmunogenA synthesized peptide derived from human Caspase 1 (Phospho-Ser376)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionThiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
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Western blot analysis of Caspase 1 (Phospho-Ser376) expression in 293 cells
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