Phospho-Catenin- beta (Tyr489) Antibody
Source: Rabbit pAb Catalog No. : CY6084
Phospho-Catenin- beta (Tyr489) Antibody (CY6084)
UniProt:P35222
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6084
数据表
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UniProt
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Mol Weight92kDa
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Alternative NamesCATNB, CTNB1, CTNNB, catenin, beta
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ImmunogenA synthesized peptide derived from human Catenin- beta around the phosphorylation site of Tyrosine 489
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionBeta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
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Western blot analysis of extracts from COS cells, treated with UV (15mins), using Catenin-β (Phospho-Tyr489) antibody. -
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Catenin-β (Phospho-Tyr489) antibody.
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