Phospho-C-RAF (Ser621) Antibody
Source: Rabbit pAb Catalog No. : CY6141
Phospho-C-RAF (Ser621) Antibody (CY6141)
UniProt:P04049
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6141
数据表
-
UniProt
-
Mol Weight74kDa
-
Alternative NamesC-RAF, C-Raf, CRAF, EC 2.7.11.1, Protein kinase raf 1, RAF proto-oncogene serine/threonine-protein kinase, RAF-1, RAF1, Raf proto-oncogene serine/threonine-protein kinase, Raf-1, Similar to murine leukemia viral (V-raf-1) oncogene homolog 1, kinase Raf1
-
ImmunogenA synthesized peptide derived from human C-RAF around the phosphorylation site of Serine 621
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityPolyclonal
-
DescriptionRaf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn
Applications
-
ReactivityHuman,Mouse,Rat
-
ApplicationWB,IHC,ICC/IF
-
Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
-
Western blot analysis of C-RAF phosphorylation expression in UV treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
销售咨询
一键电话