Phospho-GSK3 alpha (Ser21) Antibody
Source: Rabbit pAb Catalog No. : CY6246
Phospho-GSK3 alpha (Ser21) Antibody (CY6246)
UniProt:P49840
Application:WB,IHC,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6246
数据表
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UniProt
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Mol Weight51kDa
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Alternative NamesDKFZp686D0638; glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A
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ImmunogenA synthesized peptide derived from human GSK3 alpha around the phosphorylation site of Serine 21
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionGSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,IP
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200 IP
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Western blot analysis of extracts from ovary cancer cells. Line1: Using GSK3α (Phospho-Ser21) Antibody; Line2: The same antibody preincubated with synthesized phosphopeptide. -
Immunohistochemical analysis of paraffin- embedded breast carcinoma. Left: Using GSK3α (Phospho-Ser21) Antibody; Right: The same antibody preincubated with synthesized phosphopeptide.
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