Phospho-I kappaB- alpha (Ser32/Ser36) Antibody
Source: Rabbit pAb Catalog No. : CY6280
Phospho-I kappaB- alpha (Ser32/Ser36) Antibody (CY6280)
UniProt:P25963
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit pAb
References(2)
http://www.abways.cn/showproduct.asp?cid=CY6280
数据表
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UniProt
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Mol Weight39kDa
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Alternative NamesI-kappa-B-alpha, IKBA, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappaB inhibitor alpha, NFKBI, NFKBIA, RL/IF-1
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ImmunogenA synthesized peptide derived from human I kappaB- alpha around the phosphorylation site of Serine 32/Serine 36
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionNFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
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Western blot analysis of extracts from COS-7 cells, using IκB-α (Phospho-Ser32/Ser36) antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using IκB-α (Phospho-Ser32/Ser36) antibody.
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Immunofluorescence analysis of LOVO cells, using IκB-α (Phospho-Ser32/Ser36) antibody.
引用文献(2条)
Zishenwan Decreases Kidney Damage in Recurrent Urinary Tract Infection through the Inhibition of Toll-Like Receptor 4 Signal.-Evidence-based Complementary and Alternative Medicine
Study on the antidepressant effect of panaxynol through the IκB-α/NF-κB signaling pathway to inhibit the excessive activation of BV-2 microglia-Biomedicine & Pharmacotherapy