Phospho-IKK- alpha (Ser176) /IKK- beta (Ser177) Antibody
Source: Rabbit pAb Catalog No. : CY6290
Phospho-IKK- alpha (Ser176) /IKK- beta (Ser177) Antibody (CY6290)
UniProt:O15111/O14920
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAb
References（2）
http://www.abways.cn/showproduct.asp?cid=CY6290
数据表
-
UniProt
-
Mol Weight85kDa
-
Alternative NamesFLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKBKB; IKK-B; IKK-beta; IKK2; IKKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; Inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; Nuclear facto
-
ImmunogenA synthesized peptide derived from human IKK- alpha /IKK- beta around the phosphorylation site of Serine 177
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityPolyclonal
-
DescriptionIKK-beta a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.
Applications
-
ReactivityHuman,Mouse,Rat
-
ApplicationWB,IHC
-
Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
-
Western blot analysis of extracts from 3T3 cells, treated with TNF (20ng/ml, 30mins), using IKK- alpha (Phospho-Ser176)/ IKK- beta (Phospho-Ser177) antibody. -
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using IKK- alpha (Phospho-Ser176)/ IKK- beta (Phospho-Ser177) antibody.
引用文献（2条）
Euphorbia factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation in mice through the suppression of NF-κB activation.-Biochemical Pharmacology
Euphorbia Factor L2 ameliorates the Progression of K/BxN Serum-Induced Arthritis by Blocking TLR7 Mediated IRAK4/IKKβ/IRF5 and NF-kB Signaling Pathways-Frontiers in Pharmacology (Front Pharmacol)
销售咨询
一键电话