Phospho-IKK- alpha (Thr23) Antibody
Source: Rabbit pAb Catalog No. : CY6291
Phospho-IKK- alpha (Thr23) Antibody (CY6291)
UniProt:O15111
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6291
数据表
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UniProt
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Mol Weight85kDa
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Alternative NamesCHUK; conserved helix-loop ubiquitous kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkappaB kinase; IkB kinase alpha subunit; IkBKA; IKK-A; IKK-a kinase; IKK-alpha; IKK1; IKKA;
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ImmunogenA synthesized peptide derived from human IKK- alpha around the phosphorylation site of Threonine 23
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionIKK-alpha a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B, leading to their dissociation from NF-kappa-B and ultimately to their degradation. Phosphorylated and activated downstream of growth factor receptors, IL1R, and TNFR by NAK, IRAK and NIK, respectively.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
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Western blot analysis of extracts using IKKα (Phospho-Thr23) Antibody. Line1: The extracts from MDA-MB-435 cells untreated; Line2: The extracts from MDA-MB-435 cells treated with EGF. -
Immunohistochemical analysis of paraffin- embedded colon carcinoma, using IKKα (Phospho- Thr23) Antibody. Left: Untreated; Right: Treated with synthesized phosphopeptide.
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