Phospho-IKK- beta (Tyr199) Antibody
Source: Rabbit pAb Catalog No. : CY6294
Phospho-IKK- beta (Tyr199) Antibody (CY6294)
UniProt:O14920
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6294
数据表
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UniProt
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Mol Weight85kDa
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Alternative NamesEC 2.7.11.10, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK-B, IKK-beta, IKK2, IKKB, IkBKB, NFKBIKB, Nuclear factor NF-kappa-B inhibitor kinase beta, kinase IKK-beta
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ImmunogenA synthesized peptide derived from human IKK- beta around the phosphorylation site of Tyrosine 199
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionIKK-beta is a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
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Western blot analysis of extracts from HeLa cells, treated with TNF-a (20ng/ml) and Calyculin (50nM, 5mins), using IKK-β (Phospho-Tyr199) antibody. -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using IKK-β (Phospho-Tyr199) antibody.
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