Phospho-IRS-1 (Ser639) Antibody
Source: Rabbit pAb Catalog No. : CY6309
Phospho-IRS-1 (Ser639) Antibody (CY6309)
UniProt:P35568
Application:IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6309
数据表
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UniProt
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Mol WeightkDa
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Alternative NamesIRS-1, IRS1, Insulin receptor substrate-1
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ImmunogenA synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine 639
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionIRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationIHC
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Recommended dilutionIHC 1:50-1:200
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Western blot analysis of IRS-1 phosphorylation expression in whole cell lysates,The lane on the left is treated with the antigen-specific peptide. -
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using IRS-1 (phospho-Ser639) antibody.
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