Phospho-mTOR (Ser2448) Antibody
Source: Rabbit pAb Catalog No. : CY6351
Phospho-mTOR (Ser2448) Antibody (CY6351)
UniProt:P42345
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY6351
数据表
-
UniProt
-
Mol Weight289kDa
-
Alternative NamesFRAP, FRAP1, FRAP2, RAFT1, Rapamycin target protein, kinase mTOR
-
ImmunogenA synthesized peptide derived from human mTOR around the phosphorylation site of Serine 2448
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityPolyclonal
-
Descriptionan atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Applications
-
ReactivityHuman,Mouse,Rat
-
ApplicationWB,IHC
-
Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
-
Western blot analysis of extracts from Hela cells treated with EGF (200ng/ml, 30mins), using mTOR (phospho-Ser2448). -
Immunohistochemical analysis of paraffin-embedded human brain tissue using mTOR (phospho-Ser2448) antibody.
引用文献（1条）
The enhancement of Tetrandrine to gemcitabine-resistant PANC-1 cytochemical sensitivity involves the promotion of PI3K/Akt/mTOR-mediated apoptosis and AMPK-regulated autophagy-Acta Histochemica
销售咨询
一键电话