Phospho-NF- kappaB p105/p50 (Ser337) Antibody
Source: Rabbit pAb Catalog No. : CY6362
Phospho-NF- kappaB p105/p50 (Ser337) Antibody (CY6362)
UniProt:P19838
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6362
数据表
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UniProt
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Mol Weight105kDa
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Alternative NamesDNA-binding factor KBF1, EBP-1, NF-kappa-B1 p84/NF-kappa-B1 p98, NFKB1, NFkB-p50, Nuclear factor NF-kappa-B p105 subunit, nuclear factor NF-kappa-B p50 subunit
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ImmunogenA synthesized peptide derived from human NF- kappaB p105/p50 around the phosphorylation site of Serine 337
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionNFkB-p105 a transcription factor of the nuclear factor-kappaB ( NFkB) group. Undergoes cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of NFkB. NFkB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500-1:2000 IHC 1:50-1:200
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Western blot analysis of extracts from MDA-MB-435 cells using NF-κB p105/p50 (phospho-Ser337) antibody. -
Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using NF-κB p105/p50 (phospho-Ser337) antibody.
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