Phospho-Paxillin(Ser178) Antibody
Source: Rabbit pAb Catalog No. : CY6418
Phospho-Paxillin(Ser178) Antibody (CY6418)
UniProt:P49023
Application:WB
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY6418
数据表
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UniProt
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Mol Weight64kDa
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Alternative NamesPaired box protein Pax-1; PAX-1; PAXI; paxillin; paxillin alpha
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ImmunogenA synthesized peptide derived from human Paxillin around the phosphorylation site of Sersine 178
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionPXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions. The SH2 domain of Crk binds to tyrosine phosphorylated paxillin. Three alternatively-spliced isoforms have been described.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB
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Recommended dilutionWB 1:500-1:2000



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