P04629

87kDa

EC 2.7.10.1, High affinity nerve growth factor receptor precursor, NTRK1, Slow nerve growth factor receptor, TRK, TRK1 transforming tyrosine kinase protein, TRKA, Trk-A, kinase TrkA, p140-TrkA Molecular weight: 87511.17

A synthesized peptide derived from human Trk A around the phosphorylation site of Tyrosine 680+Tyrosine 681

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Polyclonal

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Human,Mouse,Rat

WB

WB 1:500-1:2000