Phospho-STAT3 (Y705) Antibody
Source: Rabbit mAb Catalog No. : CY6566
Phospho-STAT3 (Y705) Antibody (CY6566)
UniProt:P40763
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（3）
http://www.abways.cn/showproduct.asp?cid=CY6566
数据表
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UniProt
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Mol Weight88kDa
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Alternative NamesAPRF; Stat3; HIES; Acute-phase response factor;
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ImmunogenA synthesized peptide derived from human STAT3
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:5000~1:10000 IHC 1:50~1:100 ICC/IF 1:50~1:000 IP 1:30
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
Western blot analysis of Phospho-STAT3 (Tyr705) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with IFN-a. -
Immunohistochemical analysis of paraffin-embedded human pancreas, using Phospho-STAT3 (Y705) Antibody. -
Immunofluorescent analysis of HeLa cells treated with IFN-alpha, using Phospho-STAT3 (Y705) Antibody. -
Triptolide delays disease progression in an adult rat model of polycystic kidney disease through the JAK2/STAT3 pathway. -American Journal of Physiology-Renal Physiology -
Intracellular Ca2+ homeostasis and JAK1/STAT3 pathway are involved in the protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis. -plos one -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
引用文献（3条）
Intracellular Ca2+ homeostasis and JAK1/STAT3 pathway are involved in the protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis.-plos one
Triptolide delays disease progression in an adult rat model of polycystic kidney disease through the JAK2/STAT3 pathway.-American Journal of Physiology-Renal Physiology
Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1-Cell Death & Differentiation (CELL DEATH DIFFER)
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