Phospho-GSK3 (alpha + beta)(Y216 + Y279) Antibody
Source: Rabbit mAb Catalog No. : CY6567
Phospho-GSK3 (alpha + beta)(Y216 + Y279) Antibody (CY6567)
UniProt:P49840
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6567
数据表
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UniProt
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Mol Weight51kDa/46kDa
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Alternative NamesGlycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A
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ImmunogenA synthesized peptide derived from human Phospho-GSK3 (alpha + beta)(Y216 + Y279)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionGSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of GSK3 alpha/ beta phosphorylation expression in 293 cell lysate treated with AP. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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