Phospho-mTOR (S2448) Antibody
Source: Rabbit mAb Catalog No. : CY6571
Phospho-mTOR (S2448) Antibody (CY6571)
UniProt:P42345
Application:WB,IHC
Reactivity:Human,Mouse,Rat,Pig
Source:Rabbit mAb
References（6）
http://www.abways.cn/showproduct.asp?cid=CY6571
数据表
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UniProt
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Mol Weight289kDa
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Alternative NamesFRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;
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ImmunogenA synthesized peptide derived from human Phospho-mTOR (S2448)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionAn atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Applications
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ReactivityHuman,Mouse,Rat,Pig
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:1000 IHC 1:50~1:100
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Western blot analysis of Phospho-mTOR (S2448) expression in HEK293 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human breast cancer, using Phospho-mTOR (S2448) Antibody. -
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry -
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry -
Overexpression of the 14-3-3γ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis. -Cellular Signalling -
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II. -EXPERIMENTAL AND MOLECULAR MEDICINE -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
引用文献（6条）
Overexpression of the 14-3-3γ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis.-Cellular Signalling
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy.-Cellular Physiology and Biochemistry
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II.-EXPERIMENTAL AND MOLECULAR MEDICINE
Molecular hydrogen regulates PTEN‐AKT‐mTOR signaling via ROS to alleviate peritoneal dialysis‐related peritoneal fibrosis-FASEB JOURNAL (FASEB J)
CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells-Animals
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