Phospho-IRF3 (S386) Antibody
Source: Rabbit mAb Catalog No. : CY6575
Phospho-IRF3 (S386) Antibody (CY6575)
UniProt:Q14653
Application:WB,ICC/IF
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY6575
数据表
-
UniProt
-
Mol Weight47kDa
-
Alternative NamesIRF3; Interferon regulatory factor 3;
-
ImmunogenA synthesized peptide derived from human Phospho-IRF3 (S386)
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityMonoclonal
-
DescriptionMediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE.
Applications
-
ReactivityHuman
-
ApplicationWB,ICC/IF
-
Recommended dilutionWB 1:1000~1:2000 ICC/IF 1:50~1:200
-
Western blot analysis of Phospho-IRF3 (S386) expression in MCF7 cell lysate. -
SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species. -Viral Immunology -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
引用文献（1条）
SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species.-Viral Immunology
销售咨询
一键电话