eIF4EBP1 Antibody
Source: Rabbit mAb Catalog No. : CY6583
eIF4EBP1 Antibody (CY6583)
UniProt:Q13541
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6583
数据表
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UniProt
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Mol Weight18kDa
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Alternative Names4E-BP1; 4EBP1; BP-1; MGC4316; PHAS-I;
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ImmunogenA synthesized peptide derived from human eIF4EBP1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTranslation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
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Western blot analysis of eIF4EBP1 expression in K562 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using eIF4EBP1 Antibody. -
Immunofluorescent analysis of HeLa cells, using eIF4EBP1 Antibody. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature.
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