Bmi1 Antibody
Source: Rabbit mAb Catalog No. : CY6591
Bmi1 Antibody (CY6591)
UniProt:P35226
Application:WB,IHC,ICC/IF
Reactivity:Human,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6591
数据表
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UniProt
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Mol Weight40kDa
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Alternative NamesBMI1 ; Polycomb complex protein BMI 1; RING finger protein 51; RNF51; PCGF4;
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ImmunogenA synthesized peptide derived from human Bmi1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe polycomb group (PcG) of proteins contributes to the maintenance of cell identity, stem cell self-renewal, cell cycle regulation, and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death, and cell-cycle arrest. PcG proteins exist in two complexes that cooperate to maintain long-term gene silencing through epigenetic chromatin modifications. The first complex, EED-EZH2, is recruited to genes by DNA-binding transcription factors and methylates histone H3 on Lys27.
Applications
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ReactivityHuman,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
Western blot analysis of Bmi1 expression in (1) K562 cell lysate; (2) PC-12 cell lysate. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:150 dilution.
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