Argonaute 2 Antibody_单克隆抗体-上海泊湾生物技术有限公司

Argonaute 2 Antibody

Source: Rabbit mAb Catalog No. : CY6652

Argonaute 2 Antibody (CY6652)
UniProt:Q9UKV8
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6652

 Datasheet

数据表

UniProt

Q9UKV8
Mol Weight

97kDa
Alternative Names

Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD;
Immunogen

A synthesized peptide derived from human Argonaute 2
Storage

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Rabbit IgG
Clonality

Monoclonal
Description

Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.

Applications

Reactivity

Human,Mouse,Rat
Application

WB,IHC,ICC/IF,IP,FC
Recommended dilution

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Western blot analysis of Argonaute 2 expression in (1) HeLa cell lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Immunofluorescent analysis using the Antibody at 1:50 dilution.