ABCG2 Antibody
Source: Rabbit mAb Catalog No. : CY6654
ABCG2 Antibody (CY6654)
UniProt:Q9UNQ0
Application:WB
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6654
数据表
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UniProt
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Mol Weight72kDa
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Alternative NamesATP-binding cassette sub-family G member 2; Urate exporter; CD338; ABCP; BCRP; BCRP1; MXR1;
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ImmunogenA synthesized peptide derived from human ABCG2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500~1:2000
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Western blot analysis of ABCG2 expression in 293T cell lysate. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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